Our goal is to provide the mechanobiology community with tools and training to study mechanotransduction in living cells
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We are organizing a seminar series – Forces at Play: Molecular Mechanobiology Seminar Series – Sign up link
Aug. 12, 2024: “Measuring Integrin Force Loading Rates Using a Two-Step DNA Tension Sensor” is out on JACS!
Aug. 8, 2024: DNA origami tension sensors (DOTS) is now online on Nature Nanotechnology!
Feb 28, 2024: “Molecular Compressive Force Sensor for Mapping Forces at the Cell–Substrate Interface“: CRUSH is out on JACS! Open Access!
We are hiring a director of community engagement!
Jan 24, 2024: “DNA mechanocapsules for programmable piconewton responsive drug delivery“ is now online on Nature Communications! Available online.
We have started our Zoom Office Hour: Thursday 12-1 pm EST. Please request the Zoom link through Contact Us page.
Nov. 13, 2023: “Detection of cellular traction forces via the force-triggered Cas12a-mediated catalytic cleavage of a fluorogenic reporter strand“ is published on Nature Biomedical Engineering and featured by Emory News.
Aug. 13, 2023: We are officially launched! Check out the Emory News article for the details.
Announcements
The Center on Probes for Molecular Mechanobiology (CPMM) is primarily housed at Emory University in Atlanta, Georgia, as well as the University of Alabama, Birmingham, but we have collaborators and partners that are geographically spread across the USA and the globe.
The goal of our center is to develop and optimize technologies to enable the study of mechanobiology and mechanotransduction pathways in living cells. The CPMM includes three highly synergistic Technology Development Projects (TDPs) that will be led by Alexa Mattheyses, Khalid Salaita, and Yonggang Ke who have a strong scientific background in microscopy techniques, DNA mechanotechnology, and DNA nanotechnology.
